TSPO PET using 18F-GE-180: a new perspective in neurooncology?
نویسندگان
چکیده
منابع مشابه
TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis
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Introduction: The ability of quadratic dose protocol to maintain a good quality image for an overweight and obese patient is well reported. However, a practical approach to the implementation of this protocol in whole-body imaging in Malaysia is currently lacking. Hence, the aim of this study is to derive the quadratic dose formula that suits our PET system. Metho...
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BACKGROUND The activation of microglia, in general, and the upregulation of the translocator protein (18 kDa) (TSPO) system, in particular, are key features of neuroinflammation, of which the in vivo visualization and quantitative assessment are still challenging due to the lack of appropriate molecular imaging biomarkers. Recent positron emission tomography (PET) studies using TSPO radioligand...
متن کاملClinical PET/MRI in neurooncology: opportunities and challenges from a single-institution perspective
PURPOSE Magnetic resonance imaging (MRI) plays a key role in neurooncology, i.e., for diagnosis, treatment evaluation and detection of recurrence. However, standard MRI cannot always separate malignant tissue from other pathologies or treatment-induced changes. Advanced MRI techniques such as diffusion-weighted imaging, perfusion imaging and spectroscopy show promising results in discriminating...
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ژورنال
عنوان ژورنال: European Journal of Nuclear Medicine and Molecular Imaging
سال: 2017
ISSN: 1619-7070,1619-7089
DOI: 10.1007/s00259-017-3838-6